CHANGES IN BLOOD LEVELS OF TRACE ELEMENTS AND ELECTROLYTES IN HYP ERTENSIVE PATIENTS

Authors

  • AZHAR SIDDIQUE
  • M MOMTAZ
  • N MUGHAL
  • TABASSUM MAHBOOB From the Departments of Chemistry and *Biochemistry, University of Karachi, Karachi 75270, Pakistan.
Abstract:

The involvement of elements in the pathological process of primary hypertension has been established. The serum levels of copper, iron, zinc, sodium, potassium and calcium were studied by atomic absorption spectrophotometery and flame photometry in hypertensive and normal subjects. Serum copper and zinc levels were increased in hypertensive patients (25.5% and 14.7% respectively) as compared to normal subjects. A decrease in serum sodium (21".9%), potassium (31.02%), iron (44.7%) and calcium (34.23%) was observed in hypertensive as compared to control subjects. The role of these serum element variations and their possible involvement in hypertension is discussed.

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Journal title

volume 14  issue 2

pages  115- 118

publication date 2000-08

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